Senior Principal Scientist - Process Development

Lonza is hiring a Senior Principal Scientist to join our Process Development Sciences team in Singapore.

The Process Development Sciences team is a focused group of senior subject matter experts (SMEs) with deep expertise across upstream (USP), downstream (DSP), process characterization (PC), and process validation (PV). The team provides scientific and technical leadership to address both routine and complex challenges impacting process development and manufacturing.

In this role, you will collaborate across Lonza’s global mammalian network and engage directly with customers to deliver innovative, science-driven solutions. You bring broad technical experience, a passion for science, and a commitment to mentoring and knowledge sharing. You will bring a broad range of technical experience, a passion for science, and a commitment to mentoring and knowledge sharing.

This is an office-first role, enabling real-time collaboration and alignment. You will primarily work onsite, with flexibility to work remotely up to 20% of the time (1 day per week).

What you will get

• An agile career and dynamic working culture.

• An inclusive and ethical workplace.

• Compensation programs that recognize high performance.

• Daily company bus from the MRT location near your home to and from the Tuas site.

• Fully paid medical insurance, and option to enroll family members at partially subsidized premiums.

What you will do

• Provide deep scientific expertise to support development and manufacture of therapeutic proteins using mammalian cell culture across USP, DSP, PC, and PV

• Apply structured, data-driven approaches (e.g., RCA, DoE, multivariate analysis, risk assessments, FMEA) to resolve complex technical challenges and support process robustness

• Contribute to process development activities including clinical development, process transfer to cGMP, and manufacturing support

• Serve as a subject matter expert, ensuring high-quality, well-documented investigations and compliance with regulatory expectations

• Collaborate with cross-functional teams (R&D, Operations) to implement process improvements and emerging technologies

• Maintain strong scientific rigor and quality standards across customer and internal projects

• Identify and share emerging scientific, technical, and industry trends relevant to Lonza’s capabilities

• Support effective communication with customers and internal stakeholders, including presentations and technical discussions

What we are looking for

• PhD or equivalent experience in a relevant scientific discipline

• 10+ years of experience in biologics development

• Strong experience supporting late-stage clinical development, including process characterization, validation, or BLA-enabling activities

• Deep technical expertise in USP, DSP, PC, or PV

• Proven experience in data-driven problem solving, including DoE and risk-based approaches

• Demonstrated ability to lead technically across functions and global teams

• Excellent communication and stakeholder engagement skills

About Lonza

At Lonza, our people are our greatest strength. With 30+ sites across five continents, our globally connected teams work together every day to manufacture the medicines of tomorrow. Our core values of Collaboration, Accountability, Excellence, Passion and Integrity reflect who we are and how we work together. Everyone’s ideas, big or small, have the potential to improve millions of lives, and that’s the kind of work we want you to be part of.

Innovation thrives when people from all backgrounds bring their unique perspectives to the table. At Lonza, we value diversity and are committed to creating an inclusive environment for all employees. If you’re ready to help turn our customers’ breakthrough ideas into viable therapies, we look forward to welcoming you on board.

Ready to shape the future of life sciences? Apply now.