Senior Biotechnologist (Nights - A Shift)

Senior Biotechnologist - Downstream (2K Bioreactor Team)

Location: Portsmouth, NH, USA.

Join our specialized Downstream team supporting 2K bioreactor campaigns, where you will leverage your column packing expertise to execute critical purification steps and contribute to the successful manufacture of life-saving therapies.

See what a role at Lonza (Portsmouth, NH) looks like—watch this short video!

Schedule:

• Shift: Rotational Night Shift (7:00 PM – 7:00 AM)

• Pattern: 2 on, 2 off, 3 on, 2 off, 2 on, 3 off (repeating cycle)

What you will get

• An agile career and dynamic working culture.

• An inclusive and ethical workplace.

• Compensation programs that recognize high performance.

• Night and Weekend shifts include additional pay

Medical, dental and vision insurance. Our full list of global benefits can be found here: https://www.lonza.com/careers/benefits.

What you will do:

• Lead the execution of complex downstream purification unit operations, including chromatography and filtration (e.g., UF/DF systems).

• Expertly perform and document column packing procedures for various resin types to ensure optimal performance for large-scale campaigns.

• Troubleshoot equipment and process issues within the purification suite, initiating deviations and working cross-functionally to resolve them quickly.

• Demonstrate mastery of cGMP/GDP standards while executing and reviewing batch records and maintaining audit-readiness.

• Mentor and provide technical guidance to junior associates on purification techniques and process theory.

• Set up, operate, monitor, and clean large-scale purification skids and associated equipment.

• Participate in tech transfer activities and continuous improvement projects focused on enhancing downstream process efficiency.

What we are looking for:

• Education (Required Baseline): High School Diploma or equivalent is required. A Bachelor's degree in a Life Science or Engineering field is a plus.

• Specialized Experience: 3+ years of hands-on experience in downstream biomanufacturing or purification in a GMP environment is highly preferred.

• Core Technical Skill (A Plus): Proven practical expertise in column packing techniques and operation of chromatography skids is essential for success in this role.

• Process & Compliance Knowledge (A Plus): Strong general base knowledge of downstream purification principles (e.g., filtration, TFF, UF/DF) and an in-depth working knowledge of cGMP/GDP and quality systems.

• Leadership & Problem Solving (A Plus): Demonstrated ability to independently troubleshoot complex purification equipment and processes, combined with excellent communication and mentorship skills.

About Lonza

At Lonza, our people are our greatest strength. With 30+ sites across five continents, our globally connected teams work together every day to manufacture the medicines of tomorrow. Our core values of Collaboration, Accountability, Excellence, Passion and Integrity reflect who we are and how we work together. Everyone’s ideas, big or small, have the potential to improve millions of lives, and that’s the kind of work we want you to be part of.

Innovation thrives when people from all backgrounds bring their unique perspectives to the table. At Lonza, we offer equal employment opportunities to all qualified applicants regardless of race, religion, color, national origin, sex, sexual orientation, gender identity, age, disability, veteran status, or any other characteristic protected by law. If you’re ready to help turn our customers’ breakthrough ideas into viable therapies, we look forward to welcoming you on board.

Ready to shape the future of life sciences? Apply now.