Downstream Manufacturing Supervisor (Nights - A Shift)

Manufacturing Supervisor - Downstream

Location: Portsmouth, NH, USA.

Lead a dedicated team on the Night Shift (7 PM - 7 AM) supporting our high-capacity 6K Bioreactor suite, overseeing critical downstream purification processes to ensure the reliable delivery of life-changing medicines.

Schedule:

• Shift: Rotational Day Shift (7:00 AM – 7:00 PM)

• Pattern: 2 on, 2 off, 3 on, 2 off, 2 on, 3 off (repeating cycle)

• Night and Weekend shifts include additional pay.

See what a role at Lonza (Portsmouth, NH) looks like—watch this short video!

What you will get:

• An agile career and dynamic working culture.

• An inclusive and ethical workplace.

• Compensation programs that recognize high performance.

• Medical, dental and vision insurance, as well as PTO and more

Our full list of global benefits can be found here: https://www.lonza.com/careers/benefits.

What you will do:

• Supervise a group of 6-8 Manufacturing Associates, ensuring strict adherence to the production schedule and maintaining a cGMP-compliant environment at all times.

• Lead performance management and personnel development, fostering a culture of growth and accountability within your shift.

• Oversee downstream GMP operations, including equipment operation, process monitoring, and both large and small-scale buffer preparations.

• Maintain seamless communication with Upstream and Downstream suites to synchronize activities and prevent schedule disruptions.

• Review electronic documents and logbooks in accordance with Good Documentation Practices (GDPs) to ensure data integrity.

• Manage individual training plans for all direct reports, ensuring the shift remains fully qualified to execute all scheduled operations.

• Ensure the facility and equipment remain in audit-ready status through rigorous adherence to 6S programs and facility standards.

What we are looking for:

• Education: High School Diploma or Equivalent is required; an Associate’s or Bachelor’s degree in a Science-related discipline is preferred.

• Experience: Some prior supervisory or leadership exposure

• Leadership Qualities: Proven ability to make logical decisions and apply critical thinking skills in a fast-paced production environment.

• Communication: Strong written and verbal communication skills are essential for coordinating across shifts and departments.

• Cultural Alignment: Ability to live our cultural beliefs with the flexibility to adapt to changing business priorities.

• Growth Mindset: A professional who actively seeks out performance feedback and translates it into tangible improvements for themselves and their team.

About Lonza

At Lonza, our people are our greatest strength. With 30+ sites across five continents, our globally connected teams work together every day to manufacture the medicines of tomorrow. Our core values of Collaboration, Accountability, Excellence, Passion and Integrity reflect who we are and how we work together. Everyone’s ideas, big or small, have the potential to improve millions of lives, and that’s the kind of work we want you to be part of.

Innovation thrives when people from all backgrounds bring their unique perspectives to the table. At Lonza, we offer equal employment opportunities to all qualified applicants regardless of race, religion, color, national origin, sex, sexual orientation, gender identity, age, disability, veteran status, or any other characteristic protected by law. If you’re ready to help turn our customers’ breakthrough ideas into viable therapies, we look forward to welcoming you on board.

Ready to shape the future of life sciences? Apply now.