Lonza

Biotechnologist III (Nights - A Shift)

Posted Nov 17, 2025
Job ID: R71537
Location
Portsmouth, NH
Hours/week
40 hrs/week
Payrate range
Unknown
Biotechnologist III

Location: Portsmouth, NH, USA.

We are seeking a fully proficient Biotechnologist III to join our full-time, on-site production team in Portsmouth, NH, working a rotational night shift (7 PM – 7 AM). This intermediate-level role is responsible for the cGMP manufacture of therapeutic proteins (API), focusing heavily on upstream operations involving 2K bioreactors. You will independently execute process recipes, monitor equipment, and demonstrate significant knowledge of upstream process flow to troubleshoot routine and non-routine events, initiate deviations, and train other operators on specialized techniques.

Schedule:

  • Shift: Rotational Night Shift (7:00 PM – 7:00 AM)

  • Pattern: 2 on, 2 off, 3 on, 2 off, 2 on, 3 off (repeating cycle)

  • Nights and Weekend shifts include additional pay.

See what a role at Lonza (Portsmouth, NH) looks like—watch this short video!

What will you get?

  • An agile career and dynamic working culture

  • An inclusive and ethical workplace

  • Compensation programs that recognize high performance

  • Medical, dental and vision insurance, as well as PTO and more

Our full list of global benefits can be found here: https://www.lonza.com/careers/benefits.

What You’ll Do:

  • Upstream Operations & Troubleshooting: Fully proficiently set up, operate, and monitor 2K bioreactors and core production equipment (including CIP/SIP), and troubleshoot routine and non-routine equipment events within the upstream suite.

  • Specialized Lab Work & Process Flow: Independently perform specialized laboratory tasks (e.g., pH, conductivity, product sampling, media preparation) and demonstrate an in-depth understanding of upstream process flow to make experience-based decisions.

  • Documentation & Quality Review: Accurately report production activities, review batch records and logbooks, and initiate deviations in accordance with GMPs and GDPs, utilizing technical writing skills.

  • Training & Technical Mentorship: Act as a qualified trainer, mentoring other operators on assigned tasks and the scientific theory behind upstream production activities (e.g., bioreactor inoculation, large-scale cell culture).

  • Material Handling & Facility Readiness: Perform all material movements, transferring raw materials and chemicals across production areas. Maintain facility and equipment through routine cleaning, sanitization, and 6S programs.

  • Team & Administrative Support: Participate in administrative duties, including shift exchanges, meetings, and project involvement, supporting overall team compliance and effectiveness.

What We’re Looking For:

  • Education: High school diploma or equivalent is required. An AS/BS in a Science-related field is preferred.

  • Experience & Proficiency: 2–4 years of experience in upstream (fermentation/cell culture) large-scale GMP/biotech manufacturing, demonstrating full proficiency in bioreactor operations.

  • Compliance & Independence: Demonstrated ability to work independently and troubleshoot issues, possessing a significant, in-depth understanding of cGMP compliance.

  • Core Skills: Strong attention to detail, proficiency in technical writing, and effective communication skills for training and collaboration.

About Lonza


At Lonza, our people are our greatest strength. With 30+ sites across five continents, our globally connected teams work together every day to manufacture the medicines of tomorrow. Our core values of Collaboration, Accountability, Excellence, Passion and Integrity reflect who


we are and how we work together. Everyone’s ideas, big or small, have the potential to improve millions of lives, and that’s the kind of work we want you to be part of.


Innovation thrives when people from all backgrounds bring their unique perspectives to the table. At Lonza, we offer equal employment opportunities to all qualified applicants regardless of race, religion, color, national origin, sex, sexual orientation, gender identity, age, disability, veteran status, or any other characteristic protected by law. If you’re ready to help turn our customers’ breakthrough ideas into viable therapies, we look forward to welcoming you on board.


Ready to shape the future of life sciences? Apply now.

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